
Duloxetine (Cymbalta)
With our quick and easy online prescription process, you can manage your health effortlessly — whether you need a first-time prescription for Duloxetine or a refill of an existing one.
Licensed providers in all 50 states
Expert-guided, evidence-based treatments
Skip the trip to the doctor's office
Estimated pharmacy cash price
from $15/moTypical cash price for generic Duloxetine without using insurance. Estimates only — actual prices vary by location, quantity, and discount programs.
$23
CVS
$25
Walgreens
$15
Walmart
$18
Costco
Commonly prescribed for
What is Duloxetine (Cymbalta)?
SNRI for depression, anxiety, fibromyalgia, and chronic pain. Effective for both mental health and physical pain symptoms.
Dosage & forms
Drug class: SNRI (serotonin–norepinephrine reuptake inhibitor)
Typical dosing
Commonly 30–60 mg once daily; some conditions use up to 120 mg daily.
Mood and pain symptoms often improve over 4 weeks.
Your clinician determines the right dose and form for you. Always follow the instructions on your prescription label.
Common side effects
Most side effects are mild and often ease within the first few weeks. Tell your clinician if any are bothersome or do not go away.
Nausea
Dry mouth
Constipation
Fatigue
Decreased appetite
Sweating
Important safety information
Antidepressants carry a boxed warning for increased risk of suicidal thoughts in people under 25, especially in the first weeks of treatment or after a dose change. Seek help right away if mood worsens.
Use with caution with significant liver disease or heavy alcohol use due to liver injury risk.
Do not stop suddenly — your clinician will taper the dose to avoid discontinuation symptoms such as dizziness, flu-like feelings, or 'brain zaps.'
Rarely, combining serotonergic medications can cause serotonin syndrome (agitation, fast heart rate, fever, tremor). Tell your clinician about every medication and supplement you take.
This information is educational and not a complete list of risks. It is not a substitute for advice from your clinician or pharmacist. In an emergency, call 911. If you are in crisis, call or text 988.

Ongoing support, always available.
You'll be supported by experienced clinicians who care for a wide range of health needs, from everyday concerns to more complex conditions.
Our clinicians track your progress over time and adjust your care as needed. If medication is prescribed, we'll manage dosing and monitor for side effects. You're never left to navigate care on your own.
All your care in one place. That's the Attunio difference.
We help you understand your options, connect you to the right clinicians, manage prescriptions, coordinate any needed evaluations, and keep an eye on your overall health along the way.
Book a visitNot sure this care is right for you?
Share what's been going on, and we'll help you understand the right next step. When you're ready, we'll coordinate everything and make sure you have clear follow-up on your results.
What our customers have to say
“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”
“Getting my medication renewed was so easy. No waiting rooms, no scheduling hassles. Just quick, professional care.”



